Benzene exposure, assessed by urinary trans,trans-muconic acid, in urban children with elevated blood lead levels.

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منابع مشابه

Benzene exposure, assessed by urinary trans,trans-muconic acid, in urban children with elevated blood lead levels.

A pilot study was performed to evaluate the feasibility of using trans,trans-muconic acid (MA) as a biomarker of environmental benzene exposure. A secondary aim was to provide data on the extent of exposure to selected toxicants in a unique population consisting of inner-city children who were already overexposed to one urban hazard, lead. Potential sources of benzene were assessed by a questio...

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Elevated blood lead levels in Karachi children.

Editor – The recent review of environmental lead exposure (1) is timely for Karachi, where we have just completed a survey of blood lead levels in children. Our objectives were to compare current levels with those from a study done a decade ago and to assess the contribution of sources that may be amenable to intervention. The design entailed a geographically stratified urban sample of 400 chil...

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Urinary trans,trans-muconic acid as an indicator of exposure to benzene in cigarette smokers.

Epidemiological studies have shown an association between cigarette smoking and increased risk of myeloid leukemia in smokers. In evaluating this link it is important to note that cigarette smoke contains benzene, among other carcinogens. Since chronic benzene, among other carcinogens. Since chronic benzene exposure causes acute myeloid leukemia in humans, we aimed to determine the uptake and m...

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Urinary trans,trans-Muconic Acid as an Indicator of Exposure to Benzene in Cigarette Smokers1

Epidemiological studies have shown an association between cigarette smoking and increased risk of myeloid leukemia in smokers. In evaluating this link it is important to note that cigarette smoke contains benzene, among other carcinogens. Since chronic benzene exposure causes acute myeloid leukemia in humans, we aimed to determine the uptake and metabolic activation of benzene from cigarette sm...

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Occupational exposure to benzene and changes in hematological parameters and urinary trans, trans-muconic acid.

BACKGROUND For its toxicity, benzene exposure is one of the main health concerns for high risk occupations like gasoline station workers. However, there is little knowledge about the effect of benzene metabolites on hematological parameters. OBJECTIVE To evaluate the correlation between the urinary level of trans, trans-muconic acid (t, t-MA), a benzene metabolite, and some hematological para...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1996

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.96104318